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STBRL Publications

2010
2009 
2008 
2007
2006
2005
2004
Chapters in books
Other publications

2011

  1. Ison CA, Hussey J, Sankar KN, Evans J, Alexander S. Gonorrhoea treatment failures to cefixime and azithromycin in England, 2010. Euro Surveill. 2011 Apr 7;16(14).
  2. Alexander S, Coelho da Silva F, Manuel R, Varma R, Ison C. Evaluation of strategies for confirming Neisseria gonorrhoeae nucleic acid amplification tests. J Med Microbiol. 2011 Jul;60(Pt 7):909-12. Epub 2011 Mar 17.
  3. Alexander S, Coelho da Silva F, Alhadi F, Ison C. Still no evidence of new variant Chlamydia trachomatis in England and Wales. Sex Health. 2011 Mar;8(1):74-5.
  4. Chisholm SA, Quaye N, Cole MJ, Fredlund H, Hoffmann S, Jensen JS, van de Laar MJ, Unemo M, Ison CA. An evaluation of gentamicin susceptibility of Neisseria gonorrhoeae isolates in Europe. J Antimicrob Chemother. 2011 Mar;66(3):592-5.
  5. Chisholm SA, Alexander S, desouza-Thomas L, Maclure-Webster E, Anderson J, Nichols T,  Lowndes CM and Ison CA. Emergence of a Neisseria gonorrhoeae clone showing decreased susceptibility to cefixime in England and Wales. J. Antimicrob Chemother doi: 10.1093/jac/dkr332

 

2010

  1. Soni S, Srirajaskanthan R, Lucas SB, Alexander S, Wong T, White JA. Lymphogranuloma venereum proctitis masquerading as inflammatory bowel disease in 12 homosexual men. Aliment Pharmacol Ther. 2010 Mar 25. [Epub ahead of print]
  2. Benzie A, Alexander S, Gill N, Greene L, Thomas S, Ison C. Gonococcal NAATs: what is the current state of play in England and Wales? Int J STD AIDS. 2010 Apr;21(4):246-8.
  3. Chisholm SA, Dave J, Ison CA. High-level Azithromycin resistance occurs in Neisseria gonorrhoeae as a result of a single point mutation in the 23S rRNA genes.  Antimicrob Agents Chemother. 2010 Sep;54(9):3812-6
  4. Alexander S., Tosswill J. and Ison, C.I. Laboratory diagnosis of STIs. Medicine. Volume 38, Issue 5, Pages 242-244 May 2010
  5. Chisholm SA, Mouton JW, Lewis DA, Nichols T, Ison CA, Livermore DM. Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink? J Antimicrob Chemother. 2010 Aug 6
  6. Cole MJ, Chisholm SA, Hoffmann S, Stary A, Lowndes CM, Ison CA; European surveillance of antimicrobial resistance in Neisseria gonorrhoeae. Sex Transm Infect. 2010 Nov;86(6):427-32.

  7. Pope CF, Hay P, Alexander S, Capaldi K, Dave J, Sadiq ST, Ison CA, Planche T. Positive predictive value of the Becton Dickinson VIPER system and the ProbeTec GC Q x assay, in extracted mode, for detection of Neisseria gonorrhoeae. Sex Transm Infect. 2010 Nov;86(6):465-9.

  8. Ison CA, Hughes G. Gonorrhoea themed issue. Sex Transm Infect. 2010 Nov;86(6):409-11. No abstract available.

 

2009

  1. Ward H, Alexander S, Carder C, Dean G, French P, Ivens D, Ling C, Paul J, Tong C,White J, Ison CA. The prevalence of Lymphogranuloma venereum (LGV) infection in men who have sex with men: results of a multi-centre case finding study. Sex Transm  Infect. 2009 Feb 15
  2. Wayal S, Llewellyn C, Smith H, Hankins M, Phillips A, Richardson D, Fisher M; Home Sampling Kit Project Steering Group. Self-sampling for oropharyngeal and rectal specimens to screen for sexually transmitted infections: acceptability among men who have sex with men. Sex Transm Infect. 2009 Feb;85(1):60-4. Epub 2008 Aug 15
  3. Annan NT, Sullivan A, Nori A, Naydenova P, Alexander S, McKenna A, Azadian B, Mandalia S, Rossi M, Ward H, Nwokolo N. Rectal Chlamydia - A reservoir of undiagnosed infection in MSM. Sex Transm Infect. 2009 Jan 28
  4. Taylor-Robinson D, Renton A, Jensen JS, Ison CA, Filatova E, Dmitriev G, Akovbian V. Association of Mycoplasma genitalium with acute non-gonococcal urethritis in Russian men: a comparison with gonococcal and chlamydial urethritis. Int J STD AIDS. 2009 Apr;20(4):234-7.
  5. Bilek N, Ison CA, Spratt BG. Relative contributions of recombination and mutation to the diversification of the opa gene repertoire of Neisseria gonorrhoeae. J Bacteriol. 2009 Mar;191(6):1878-90. Epub 2008 Dec 29
  6. Renton A, Filatova E, Ison C, Meheus A, Dmitriev G, Akovbian V, Taylor-Robinson D. A trial of the validity of genital smears and cultures with gonococcal vaccine provocation in diagnosing genital gonorrhoea in women. Int J STD AIDS 2009 Jan;20(1):24-9
  7. Amin AK, Manuel RJ, Ison CA, Woodham R, Shemko M, Maguire H, Giraudon I, Forde J, Gillespie SH. Audit of laboratory diagnostic methods for syphilis in England and Wales. Sex Transm Infect. 2009 Apr;85(2):88-91
  10. Cole MJ, Chisholm S, Palmer HM, Wallace LA, Ison CA. Molecular epidemiology of syphilis in Scotland.  Sex Transm Infect. 2009 Jun 3. [Epub ahead of print]
  11. Chisholm SA, Neal TJ, Alawattegama AB, Birley HD, Howe RA, Ison CA. Emergence of high-level azithromycin resistance in Neisseria gonorrhoeae in England and Wales.  J Antimicrob Chemother. 2009 May 25. [Epub ahead of print] 
  12. Delpech V, Martin IM, Hughes G, Nichols T, James L, Ison CA. Epidemiology and clinical presentation of gonorrhoea in England & Wales: Findings from the Gonococcal Resistance to Antimicrobials Surveillance Programme 2001-2006.  Sex Transm Infect. 2009 Apr 20. [Epub ahead of print]
  13. Rigsby P, Ison C, Brierley M, Ballard R, Hagedorn HJ, Lewis DA, Notermans DW, Riis J, Robertson P, Seppälä IJ, Rijpkema S. Evaluation of two human plasma pools as candidate international standard preparations for syphilitic antibodies. Biologicals. 2009 Apr 16. [Epub ahead of print]
  14. Renton A, Filatova E, Ison C, Meheus A, Dmitriev G, Akovbian V, Taylor-Robinson D. Performance of direct fluorescent antibody tests for routine diagnosis of Chlamydia trachomatis in Russian sexually transmitted disease clinics.  Int J STD AIDS. 2008 Dec;19(12):851-5.
  15. Alexander S, Ison C, Parry J, Llewellyn C, Wayal S, Richardson D, Phillips A, Smith H, Fisher M; Brighton Home Sampling Kits Steering Group. Self-taken pharyngeal and rectal swabs are appropriate for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in asymptomatic men who have sex with men. Sex Transm Infect. 2008 Nov;84(6):488-92.
  16. Sethi G, Allason-Jones E, Richens J, Annan NT, Hawkins D, Ekbote A, Alexander S, White J. Lymphogranuloma venereum presenting as genital ulceration and inguinal syndrome in men who have sex with men in London, UK.  Sex Transm Infect. 2009 Jun;85(3):165-70.
  18. Ross J, Brown L, Saunders P, Alexander S. Mycoplasma genitalium in asymptomatic patients - implications for screening.   Sex Transm Infect. 2009 Jul 8. [Epub ahead of print]
  19. Nadala EC, Goh BT, Magbanua JP, Barber P, Swain A, Alexander S, Laitila V, Michel CE, Mahilum-Tapay L, Ushiro-Lumb I, Ison C, Lee HH. Performance evaluation of a new rapid urine test for chlamydia in men: prospective cohort study. BMJ. 2009 Jul 28;339
  20. Booth J, Rodger A, Singh J, Alexander S, Hopkins S. Syphilitic panuveitis with retinal necrosis in an hiv positive man confirmed by treponema pallidum PCR. J Infect. 2009 Sep 17. [Epub ahead of print]
  21. Soni S, Alexander S, Verlander N, Saunders P, Richardson D, Fisher M, Ison C. The prevalence of urethral and rectal Mycoplasma genitalium and its associations in men who have sex with men attending a genitourinary medicine clinic. Sex Transm Infect. 2009 Oct 19. [Epub ahead of print]
  22. Savage EJ, van de Laar MJ, Gallay A, van der Sande M, Hamouda O, Sasse A, Hoffmann S, Diez M, Borrego MJ, Lowndes CM, Ison C, Surveillance of Sexually Transmitted Infections (ESSTI) network.  Lymphogranuloma venereum in Europe, 2003-2008. European Euro Surveill. ;14(48). pii: 19428.PMID: 20003898 [PubMed - in process]
  23. Savage EJ, Hughes G, Ison C, Lowndes CM; European Surveillance of Sexually Transmitted Infections network. Syphilis and gonorrhoea in men who have sex with men: a European overview. Euro Surveill. 2009 Nov 26;14(47). pii: 19417.PMID: 19941803 [PubMed - in process]

2008

  1. De Jongh M, Dangor Y, Ison C, Hoosen A. Neisseria gonorrhoeaemulti-antigen sequence typing (NG-MAST) of ciprofloxacin resistant isolates of Pretoria, South Africa. J Clin Pathol 2008;61:686-7
  2. Alexander S, Ison CA. Is new variant Chlamydia trachomatis present in England and Wales? Sex Transm Infect 2008; 84:29-31
  3. Chisholm SA, Ison C. Emergence of high-level azithromycin resistance in Neisseria gonorrhoeae in England and Wales.Euro Surveill. 2008 Apr 10;13(15) pii: 18832.]
  4. Greene L, Rubinstein L, Gaffney J, Rebec M, Alexander S, Ison C. Lymphogranuloma venereumin the UK in 2003. Int J STD AIDS. 2008 Feb;19(2):139-40.
  5. Chen CY, Chi KH, Alexander S, Ison C, Ballard RC. A real-time quadriplex PCR assay for the diagnosis of rectal Lymphogranuloma venereum (LGV) and non-LGV Chlamydia trachomatis infections. Sex Transm Infect. 2008 Feb 18. [Epub ahead of print]
  6. Alexander S, Martin IM, Ison C. A comparison of two methods for the diagnosis of Lymphogranuloma venereum. J Med Microbiol. 2008 Aug;57(Pt 8):962-5.
  7. White, J. & Ison, C.A. Lymphogranuloma venereum: what does the clinician need to know? (2008) Clinical Medicine Vol 8 No 3.
  8. Amin AK, Manuel RJ, Ison CA, Woodham R, Shemko M, Maguire H, Giraudon I, Forde J, Gillespie SH. Audit of laboratory diagnostic methods for syphilis in England and Wales. Sex Transm Infect. 2008 Nov 12. PMID: 19004864
  9. Alexander S, Ison C, Parry J, Llewellyn C, Wayal S, Richardson D, Phillips A, Smith H, Fisher M; Brighton Home Sampling Kits Steering Group. Self-taken pharyngeal and rectal swabs are appropriate for the detection of Chlamydia trachomatis and Neisseria gonorrhoeae in asymptomatic men who have sex with men. Sex Transm Infect. 2008 Nov;84(6):488-92
  10. Renton A, Filatova E, Ison C, Meheus A, Dmitriev G, Akovbian V, Taylor-Robinson D. Performance of direct fluorescent antibody tests for routine diagnosis of Chlamydia trachomatis in Russian sexually transmitted disease clinics. Int J STD AIDS. 2008 Dec;19(12):851-5
  11. Sethi G, Allason-Jones E, Richens J, Annan NT, Hawkins D, Ekbote A, Alexander S, White J. Lymphogranuloma venereum presenting as genital ulceration and inguinal syndrome in men who have sex with men in London, United Kingdom.   Sex Transm Infect. 2008 Dec 9. [Epub ahead of print]

2007

  1. Ward H, Martin I, MacDonald N, Alexander S, Simms I, Fenton K, French P, Dean G, Ison C. Lymphogranuloma venereum in the United Kingdom. Clin Infect Dis 2007;44:26-32
  2. Martin IM, Foreman E, Hall V, Nesbitt A, Forster G, Ison CA. Non-cultural detection and molecular genotyping of Neisseria gonorrhoeae from a piece of clothing. J Med Microbiol. 2007;56:487-90
  3. Jebbari H, Alexander S, Ward H, Evans B, Solomou M, Thornton A, deans G, White J, French PD, Ison CA. Update on Lymphogranuloma venereum in the UK. Sex Transm Infect 2007;83:324-26
  4. Magbanua JP, Goh BT, Michel CE, Aguirre-Andreasen A, Alexander S, Ushiro-Lumb, Ison C, Lee H. Chlamydia trachomatis variant not detected by plasmid-based nucleic acid amplification test: Molecular characterisation and failure of a single dose of azithromycin. Sex Transm Infect 2007;0:sti.026435v1
  5. Alexander S, Martin IM, Ison CA. Confirming the Chlamydia trachomatis status of referred rectal specimens. Sex Transm Infect 2007;83:327-9
  6. Hamill M, Benn P, Carder C, Copas A, Ward H, Ison C, French P. The clinical manifestations of anorectal infection with lymphogranuloma venereum (LGV) versus non-LGV strains of Chlamydia trachomatis: a case control study in homosexual men. Int J STD AIDS 2007;18:472-5
  7. Chen C-Y, Chi K-H, Alexander SA, Martin IMC, Lui H, Ison CA, Ballard RC. The molecular diagnosis of Lymphogranuloma venereum: evaluation of a Real-Time multiplex polymerase chain reaction test using rectal and urethral specimens. Sex Transm Dis 2007;34:451-5
  8. Jalal H, Stephen H, Alexander S, Carne C, Sonnex C. Development of real-time PCR assays for genotyping of Chlamydia trachomatis. J Clin Microbiol. 2007;45(8):2649-53.
  9. Savage EJ, Ison CA, van de Laar MJ, ESSTI network. Results of a Europe-wide investigation to assess the presence of a new variant of Chlamydia trachomatis. Euro Surveill 2007;12(10):E3-4
  10. Mahilum-Tapay L, Laitila V, et al. New point of care Chlamydia Rapid test- bridging the gap between diagnosis and treatment:performance evaluation study. Br Med J 2007; 335:1190-4
  11. Risley CL, Ward H, Choudhury B, Bishop CJ, Fenton KA, Spratt BG, Ison CA, Ghani AC. Geographical and demographic clustering of gonorrhoea in London. Sex Transm Infect. 2007 Oct;83(6):481-7.
  12. Bilek N, Martin IM, Bell G, Kinghorn GR, Ison CA, Spratt BG. Concordance between Neisseria gonorrhoeae genotypes recovered from known sexual contacts. J Clin Microbiol. 2007 Nov;45(11):3564-7
  13. van de Laar M, Ison C. Europe-wide investigation to assess the presence of new variant of Chlamydia trachomatis in Europe. Euro Surveill. 2007 Feb 8;12(2):E070208.4

2006

  1. Herida M, Descenclos J-C, Martin IMC, Goulet V, Laurent E, Sednaoui P. Increase of Neisseria gonorrhoeae ciprofloxacin resistance in France in 2001-2003. Sex Transm Dis 2006;33:6-7
  2. Bozicevic I, Fenton KA, Martin IM, Rudd EA, Ison CA, Nanchahal K, Wellings K. Epidemiological correlates of asymptomatic gonorrhoea. Sex Transm Dis. 2006(Mar 21); 33:289-95.
  3. Moodley P, Martin IM, Pillay, Ison CA, Sturm AW. Molecular epidemiology of recently emerged ciprofloxacin-resistant Neisseria gonorrhoeae in South Africa. Sex Transm. 2006; 33:357-60.
  4. Ison CA. Commentary on lymphogranuloma venereum. Sex Transm Infect. 2006 82:141
  5. Choudhury B, Risley CL, Ghani AC, Bishop CJ, Ward H, Fenton KA, Ison CA, Spratt BG. Identification of individuals with gonorrhoea within sexual networks: a population-based study. Lancet Infectious Diseases 2006 368: 139-146.
  6. Ison CA, Martin IMC, Lowndes CM, Fenton KA on behalf of the European Surveillance of Sexually Transmitted Infections (ESSTI) network. Comparability of laboratory diagnosis and antimicrobial susceptibility testing of Neisseria gonorrhoeae from reference laboratories in Western Europe. J Antimicrob Chemother 2006 (Jun 27) 58:580-6
  7. Martin IMC, Hoffmann S, Ison CA on behalf of the European Surveillance of Sexually Transmitted Infections (ESSTI) network. European Surveillance of Sexually Transmitted Infections (ESSTI): the first combined antimicrobial susceptibility data for Neisseria gonorrhoeae in Western Europe. J Antimicrob Chemother. 2006(Jul 1) 58:587-93
  8. Alexander SA, Martin IMC, Fenton K, Ison C. The prevalence of proline iminopeptidase negative Neisseria gonorrhoeae throughout England & Wales. Sex Transm Infect. 2006; 82: 280-282
  9. Martin IM, Alexander SA, Ison CA, Macdonald N, Ward H. Diagnosis of lympogranuloma venereum (LGV) from biopsy samples. Gut 2006 ; 55:1522-3
  10. Simms I, Ward H, Martin I, Alexander S, Ison C. Lymphogranuloma venereum in Australia. Sex Health 2006;3:131-3
  11. Chen CY, Chi KH, Alexander S, Martin IM, Liu H, Ison CAS, Ballard RC. The molecular diagnosis of lymphogranuloma: Evaluation of real-time multiplex PCR test using rectal and urethral specimens. Sex Transm Dis 2006.
  12. Ross JD, Ison C, Radcliffe KW. A paradigm shift in testing for sexually transmitted infections. Sex Transm Infect. 2006;82:424-5
  13. Ison C. GC NAATs: is the time right? Sex Transm Infect. 2006;82:515
  14. Ross JD, Ison CA. UK national screening and testing guidelines for sexually transmitted infections. Introduction and summary tables. Sex Transm Infect. 2006;82 Suppl 4:iv1-iv5
  15. Keane F, Ison CA, Noble H, Estcourt C. UK national screening and testing guidelines for sexually transmitted infections. Bacterial vaginosis. Sex Transm Infect. 2006;82 Suppl 4:iv16-iv18
  16. Lewis DA, Ison CA. UK national screening and testing guidelines for sexually transmitted infections. Chancroid. Sex Transm Infect. 2006;82 Suppl 4:iv19-iv520
  17. Bignell C, Ison CA, Jungmann E. UK national screening and testing guidelines for sexually transmitted infections. Gonorrhoea. Sex Transm Infect. 2006;82 Suppl 4:iv6-iv9

2005

  1. Alexander S, Ison C. Evaluation of commercial kits for the identification of Neisseria gonorrhoeae. Journal of Medical Microbiology ; 2005 54(9)(Sept) ; 827-831.
  2. French P, Ison CA, Macdonald N. Lymphogranuloma venereum in the United Kingdom. Sexually Transmitted Infections ; 2005 81(2)(Apr) ; 97-98.
  3. Macdonald N, Ison C, Martin I, Alexander S, Lowndes C, Simms I, Ward, H. Initial results of enhanced surveillance for lymphogranuloma venereum (LGV) in England. Eurosurveillance ; 2005 10(1-3) (Jan.-Mar); 57.
  4. Ragunathan PL, Ison C, Livermore DM. Nalidixic acid-susceptible, ciprofloxacin-resistant Neisseria gonorrhoeae strain in the UK. Journal of Antimicrobial Chemotherapy ; 2005 56(2)(Aug) ; 437.
  5. Martin IM, Ison CA, Aanensen D, Fenton KA, Spratt BG. Changing Epidemiologic Profile of Quinolone-Resistant Neisseria gonorrhoeae in London. Journal of Infectious Diseases. 2005 (Oct 1);192 (7):1191-1195.
  6. Palmer HN, Young H, Martin IM, Ison CA, Spratt BG. The epidemiology of ciprofloxacin resistant isolates of Neisseria gonorrhoeae in Scotland 2002: a comparison of phenotypic and genotypic analysis. Sexually Transmitted Infections. 2005;8(5):403-7.

2004

  1. Ison CA, Mouton JW, Jones K, Fenton KA, Livermore DM, North Thames Audit group. Which cephalosporin for gonorrhoea? Sexually Transmitted Infections. 2004 Oct;80(5):386-8.

Chapters in books

  1. Ison CA and Ross JR. The Management of Antibiotic Resistant Neisseria gonorrhoeae. Ch 9 in Management of Multiple Drug-Resistant Infections. Gillespie SH.ed. (Humana Press Inc, New Jersey, USA) 2004;159-172
  2. Ison CA. Bacterial Infections of the genital tract. Ch 25 in Topley & Wilson's Microbiology and Microbial Infections 10th Edition. Borriello SP, Murray PR, Funke G eds (Holder Arnold, London) 2005;657-671
  3. Ison CA. Neisseria gonorrhoeae. Ch 15 in Principles and Practice of Clinical Bacteriology Second Edition. Gillespie SH, Hawkey PM. (John Wiley & Sons Ltd, England) 2006;221-230

  4. Alexander S. and Anderson M. The laboratory diagnosis and point of care tests for STIs. The ABC of STIs. 6th Edition. BMJ Books.

  5. Alexander S, Tosswill J, Ison CA. Laboratory diagnosis of sexually transmitted infections Medicine (2010).

Other publications

  1. GRASP Steering Group.The Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP), Year 2003 Collection.  London, Health Protection Agency 2004.
  2. GRASP Steering Group. The Gonococcal Resistance to Antimicrobials Surveillance Programme GRASP), Year 2004 Collection.  London, Health Protection Agency 2005.
  3. GRASP Steering Group. The Gonococcal Resistance to Antimicrobials Surveillance Programme GRASP), Year 2005 Collection.  London, Health Protection Agency 2006.
  4. GRASP Steering Group. The Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP), Year 2006 Collection. London, Health Protection Agency 2007.
  5. GRASP Steering Group. The Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP), Year 2007 Collection. London, Health Protection Agency 2008.
  6. Chlamydia trachomatis NAAT Evaluation.  (PDF 312kB) http://www.pasa.nhs.uk/pasa/Doc.aspx?Path=% 5BMN%5D%5BSP%5D/NHSprocurement/CEP/Microbiology/Report06054.pdf  Health Protection Agency, May 2008. 
  7. GRASP Steering Group. The Gonococcal Resistance to Antimicrobials Surveillance Programme (GRASP), Year 2008 collection. London, Health Protection Agency 2009.
  8. A summary report on the 2009 GRASP data is available in the HPA's Health Protection Report.