ESBL references

Journal papers and conference posters

• 2006
• 2005
• 2004
• 2003

Guidelines can be found under the Guidance section of the website.

2006

• Woodford N, et al. Wide geographic spread of diverse acquired AmpC beta-lactamases among Escherichia coli and Klebsiella spp. in the UK and Ireland. J Antimicrob Chemother. 2006 Nov 6; [Epub ahead of print]

• Woodford N, et al. Molecular epidemiology of multiresistant Escherichia coli isolates from community-onset urinary tract infections in Cornwall, England. J Antimicrob Chemother. 2006 Nov 6; [Epub ahead of print

• Potz N, et al. Prevalence and mechanisms of cephalosporin resistance in Enterobacteriaceae in London and South-East England. J Antimicrob Chemother. 2006 Aug; 58: 320-326.

• Thomas K, et al. Activity of mecillinam against ESBL producers in vitro. J Antimicrob Chemother. 2006 Jul; 57: 367-8.

• Elliott F, et al. In-vivo development of ertapenem resistance in a case of pneumonia caused by Klebsiella pneumoniae with an extended-spectrum beta-lactamase. Clin Infect Dis. 2006 Jun; 42(11); e95-e98.

• Livermore D, et al. Activity of temocillin versus prevalent ESBL- and AmpC-producing Enterobacteriaceae from SE England. J Antimicrob Chemother. 2006 May; 57; 1012-4.

• Sinha A, et al. Early onset Morganella morganii sepsis in a newborn infant with emergence of cephalosporin resistance caused by derepression of Ampc beta-lactamase production. Pediatr Infect Dis J. 2006 Apr; 25: 376-7.

• Ellington et al. Mutators among UK CTX-M beta-lactamase-producing pose a risk for the emergence of fosfomycin resistance (PDF, 636 KB)(poster) 16th European Congress of Clinical Microbiology and Infectious Diseases; 2006 April 1- 4; Nice, France

• Ensor et al. Novel reverse hybridisation assay to identify CTX-M genotype in cephalosporin-resistant isolates from UK and India. 16th European Congress of Clinical Microbiology and Infectious Diseases; 2006 April 1- 4; Nice, France

• Hope R, et al. Efficacy of practised screening methods for selection of cephalosporin-resistant Enterobacteriaceae (PDF, 474 KB) (poster) 16th European Congress of Clinical Microbiology and Infectious Diseases; 2006 April 1- 4; Nice, France

• Karisik et al. Uncommon CTX-M enzyme variants in the United Kingdom. (PDF, 820 KB) (poster) 16th European Congress of Clinical Microbiology and Infectious Diseases; 2006 April 1- 4; Nice, France

• Karisik et al. Differential expression of CTX-M-15 beta-lactamase between two major Escherichia coli strains in the UK. (PDF, 817 KB) (poster)16th European Congress of Clinical Microbiology and Infectious Diseases; 2006 April 1- 4; Nice, France

• Pillay D, et al. Therapy-driven selection of carbapenem resistance in CTX-M-producing (PDF, 851 KB) (poster) 16th European Congress of Clinical Microbiology and Infectious Diseases; 2006 April 1- 4; Nice, France

• Woodford et al.  Wide geographic spread of diverse acquired AmpC beta-lactamases in Escherichia coli and Klebsiella spp. in the UK and Ireland (PDF, 541 KB) (poster) 16th European Congress of Clinical Microbiology and Infectious Diseases; 2006 April 1- 4; Nice, France

• Eisner A, et al. Emergence of CTX-M extended-spectrum beta-lactamase-producing Enterobacteriaceae in Austria. Antimicrob. Agents Chemother. 2006 Feb ; 50:785-7.

• Woodford N, et al. Multiplex PCR for rapid detection of genes encoding CTX-M extended-spectrum beta-lactamases. J Antimicrob Chemother. 2006 Jan; 57;154-5.

2005

• Birkett et al. Real-Time TaqMan PCR Method for the Detection and Characterisation of CTX-M Genotypes in Extended Spectrum Beta-Lactamase (ESBL)-Producing Enterobacteriaceae . 45th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2005 Dec; Washington, USA.

• Hope R, et al. Activity of tigecycline against ESBL- & AmpC- hyperproducing Enterobacteriaceae (poster) 45th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2005 Dec; Washington, USA.

• Hope R, et al. Prevalence of Mechanisms Responsible for Cephalosporin Resistance in Enterobacteriaceae from Southeast England. (poster) 45th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2005 Dec; Washington, USA.

• Woodford N, et al. ACC-1 AmpC beta-Lactamase in K. pneumoniae and E. coli Isolates from Two Dublin Hospitals. (poster) 45th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2005 Dec; Washington, USA.

• Samuel J, et al. Disagreements between disc diffusion, and MIC-based susceptibility categorizations of ertapenem versus ESBL producers. J Antimicrob Chemother. 2005 Nov; 56(5): 984-5.

  • Livermore D, et al. CTX-M changing the face of ESBLs in the UK. J Antimicrob Chemother. 2005 Sep; 56(3): 451-4.

  • Robinson E, et al. A comparison of the detection and reporting practices of ESBL-producing E. coli infections in English microbiology laboratories between 2002-3 and 2004-5. (poster) Health Protection Agency Annual Conference; 2005 Sep; Warwick, UK.

  • Ellington M, et al. Accelerated development of TEM-29 extended-spectrum beta-lactamase from TEM-1 in hypermutable, mutS, E. coli. (poster) 15th European Congress of Clinical Microbiology and Infectious Diseases; 2006 Apr; Copenhagen, Denmark.

  • Ellington M, et al. Elevated frequency of second-step ceftazidime resistance in hypermutable MutS-negative E. coli harbouring an extended-spectrum beta-lactamase. [poster] 15th European Congress of Clinical Microbiology and Infectious Diseases; 2006 Apr; Copenhagen, Denmark.

  • Fagan E, et al. Characterisation of Escherichia coli producing CTX-M-9-like beta-lactamases in the UK. (poster) 15th European Congress of Clinical Microbiology and Infectious Diseases; 2006 Apr; Copenhagen, Denmark.

  • Glasswell A, et al. Ascertainment of ESBL-producing E. coli infections in 2002 and 2003 - survey of English microbiology laboratories. (poster) 15th European Congress of Clinical Microbiology and Infectious Diseases; 2006 Apr; Copenhagen, Denmark.

  • Karisik E, et al. Molecular characterisation of plasmids from CTX-M-15-producing Escherichia coli strains responsible for outbreaks in the United Kingdom. [poster] 15th European Congress of Clinical Microbiology and Infectious Diseases; 2006 Apr; Copenhagen, Denmark.

  • Ward M, et al. Carbapenem-resistant, CTX-M-producing Klebsiella pneumoniae in the UK. [poster] 15th European Congress of Clinical Microbiology and Infectious Diseases; 2006 Apr; Copenhagen, Denmark.

  • Woodford N, et al. Development of a mutiplex PCR assay for genes encoding CTX-M extended-spectrum beta-lactamases. [poster] 15th European Congress of Clinical Microbiology and Infectious Diseases; 2006 Apr; Copenhagen, Denmark.

  • Teale C, et al. Extended-spectrum beta-lactamase detected in E. coli recovered from calves in Wales. Vet Rec. 2005 Feb; 156(6): 186-7.

  2004

  • Winstanley T, et al. First isolation of a CTX-M-3 beta-lactamase producer in the United Kingdom. Internat. J. Antimicrob. Agents. 2004 Dec, 24(6); 625-627.

  • Ellington M, et al. "Accelerated development of extended-spectrum ??-lactamase activity in hypermutable, mutS, Escherichia coli." (PDF, 554 KB)
    
    [poster]  44th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2004 Oct; Washington, USA.

  • Livermore D, et al. Inconsistent cephalexin resistance of CTX-M-15-producing strains prevalent in the UK implications for detection. (PDF, 356 KB)
    
    [poster]  44th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2004 Oct; Washington, USA.

  • Woodford N, et al. Community and hospital spread of Escherichia coli producing CTX-M extended-spectrum {beta}-lactamases in the UK. J. Antimicrob. Chemother. 2004 Oct; 54(4): 735-743.

  • Warren R, et al. A simultaneous bi-clonal outbreak of urinary infection with E. coli O25 with extended-spectrum ??-lactamase CTX-M-15: community and hospital consequences in two English Health Districts [poster] 14th European Congress of Clinical Microbiology and Infectious Diseases; 2004 May; Prague, Czech Republic.

  • Woodford N, et al. Inconsistent cephalexin resistance of CTX-M-15-producing strains prevalent in the UK implications for detection. (PDF, 356 KB)
    
    (poster) 14th European Congress of Clinical Microbiology and Infectious Diseases; 2004 May; Prague, Czech Republic.

  • Essack S, et al. Klebsiella pneumoniae isolate from South Africa with multiple TEM, SHV and AmpC beta-lactamases. Int. J. Antimicrob. Agents 2004 Apr; 23(4): 398-400.

  • Mushtaq S, et al. Comparative activity of doripenem vs. Enterobacteriaceae and Acinetobacter isolates, mutants and transconjugants with characterized beta-lactamases. Antimicrob. Agents Chemother. 2004 Apr; 48(4): 1313-9.

  • Potz N, et al. False-positive extended-spectrum beta-lactamase tests for Klebsiella oxytoca strains hyperproducing K1 beta-lactamase. J. Antimicrob. Chemother. 2004 Mar; 53(3): 545-7.

  • Johnson A, et al. The increasing problem of cephalosporin resistance mediated by extended-spectrum beta-lactamases. Curr Opin Investigat Drugs 2004 Feb; 5(2): 133-4.

  • Livermore D, et al. Should third-generation cephalosporins be avoided against AmpC-inducible Enterobacteriaceae? Clin. Microbiol. Infect. 2004 Jan; 10(1): 84-5.

  2003

  • Alobwede I, et al. CTX-M extended-spectrum beta-lactamase arrives in the UK. J. Antimicrob. Chemother. 2003 Feb; 51(2): 470-1.

  • Babini G, et al. Variable susceptibility to piperacillin/tazobactam amongst Klebsiella spp. with extended-spectrum beta-lactamases. J. Antimicrob. Chemother. 2003 Mar; 51(3): 605-12.

  • Livermore D, et al. Properties and potential of ertapenem. J. Antimicrob. Chemother. 2003 Sep; 52(3): 331-44.

  • Mushtaq S, et al. Detection of CTX-M-15 extended-spectrum beta-lactamase in the United Kingdom. J. Antimicrob. Chemother. 2003 Sep; 52(3); 528-529.

  • Mushtaq S, et al. Detection of CTX-M-15 extended-spectrum beta-lactamase (ESBL) in the UK. [poster]14th European Congress of Clinical Microbiology and Infectious Diseases; 2003 May; Glasgow, UK.