HPA programme of research in human biomonitoring

The HPA is developing a programme of work relating to human biomonitoring. Of particular interest is the investigation of the applicability of human biomonitoring to investigate acute exposure following a chemical incident. The HPA, assisted by the Laboratory Review and Liaison Group (LRLG), is producing guidance for 20 chemicals of particular interest, the first 10 of which are the most common chemicals from incidents reported between 1998 and 2000. Another area relates to the need for reliable background data on "normal" level of chemicals in blood and other tissues.

• Guidance on the use of biomonitoring in chemical incidents
  

To assess exposure following chemical incidents, samples can be taken, where appropriate and feasible, from the general public living in the vicinity of the incident and/or from people at direct risk of exposure e.g. those involved in the incident

• Laboratory Review and Liaison Group
  

The HPA coordinates a collaborative group called The Laboratory Review and Liaison Group (LRLG).

• Reference range study
  

Gathering data on the background levels of chemicals in blood and other tissues of the general population

European biomonitoring studies

The HPA is the UK lead for the consortium to perform human biomonitoring on a European scale (COPHES). In December 2009, COPHES began work towards an EU Human Biomonitoring framework. The aim is to develop a coherent approach to human biomonitoring in Europe. COPHES is accompanied by a feasibility study called DEMOCOPHES, which started in autumn 2010. http://www.eu-hbm.info

Speculative studies

Finally the HPA plans to be involved, where appropriate, in ad hoc studies to investigate specific questions. For example, uptake of certain metals around contaminated sites.

Research in human biomonitoring may also provide a useful tool in refining exposure estimates in epidemiological studies.
 

Last reviewed: 15 July 2011