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Home Publications Infectious diseases HIV and sexually transmitted infections ›  Gonoccocal resistance to antimicrobials surveillance programme (GRASP) action plan for England and Wales: informing the Public Health Response

Gonoccocal resistance to antimicrobials surveillance programme (GRASP) action plan for England and Wales: informing the Public Health Response

Gonoccocal Resistance to Antimicrobials Surveillance Programme (GRASP) Action Plan for England and Wales

Authors:

Health Protection Agency

Publication date: February 2013

 

Synopsis

  • Public health control of gonorrhoea is dependent of the provision of effective antimicrobial therapy and has been compromised by resistance to successive therapeutic agents over decades.
  • Surveillance data has shown a drift towards decreased susceptibility to the third generation cephalosporins currently recommended for therapy — ceftriaxone and cefixime.
  • Therapeutic failure to ceftriaxone and cefixime is still rare but is documented.
  • The WHO Global Action Plan and ECDC Response Plan have been published to provide strategic advice on the threat of MDR gonorrhoea.
  • National guidelines have been published in response to this threat and TOC is recommended.
  • The GRASP Action plan aims to raise awareness and provide advice on the international problem of antimicrobial resistant gonorrhoea. Case definitions have been recommended for confirmed and probable treatment failure.

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Additional information

For further information please visit the GRASP page.

Last reviewed: 26 February 2013