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Acetonitrile

Key Points

Fire

  • Highly flammable
  • Reacts with reacts with strong oxidants causing fire and explosion hazards
  • Emits toxic fumes of hydrogen cyanide and nitrogen oxides when heated to decomposition
  • In the event of a fire involving acetonitrile, use alcohol resistant foam, or fine water spray if not available, and normal fire kit with breathing apparatus

Health

  • Toxic via ingestion, inhalation or dermal contact
  • CHIP: highly flammable, harmful and irritant
  • Early features include headache, nausea, dizziness and anxiety followed by confusion, drowsiness, tachycardia, palpitations and tachypnoea 
  • In cases of moderate toxicity there may be brief episodes of loss of consciousness, convulsions, vomiting, profound lactic acidosis and hypotension 
  • In severe poisoning deep coma, fixed unreactive pupils, cardiovascular collapse, respiratory depression, myocardial ischaemia, cardiac arrhythmias and pulmonary oedema may develop

Environment

  • Avoid release into the environment
  • Inform Environment Agency of substantial release incidents

 

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