From within the HPA these are the Immunisation Department, the Gloucester Vaccine Evaluation Unit, the Manchester Vaccine Evaluation Laboratory and the Immunoassay Group. From outside the HPA these are the Institute of Child Health and the National Institute for Biological Standards and Control. For some trials we also work with specific partners who provide facilities and expertise to enhance the core structure of the NVEC, including universities and acute hospital trusts.

If you would like to see information about the trials the we are running at the moment please select the appropriate link below. Please note that participation in our studies can be dependent upon which area of the country you live in, and in some cases which surgery you attend, as we only have approval and staff in place in certain locations.  If you have any questions relating to the trials listed, please contact the Clinical Trials Team at Clinical.Trials@hpa.org.uk.

Current Studies

Pneumococcal carriage study (pneumocast)

• Parent information leaflet (PDF, 87 KB)

Study following pre-school booster vaccination (DIPS)

• Parent information leaflet (Word Document, 60 KB)

 Study of infant vaccination schedule (Sched2)

• Sched2 treatment schedule (Word Document, 31 KB)
• Parent information leaflet.pdf (PDF, 99 KB)

Head to Head Study of the two HPV vaccines

• HPV Vaccination Study (PDF, 119 KB)

Swine Flu (Novel Influenza A H1N1) Clinical Trial in Children (6 months to 12 years)

The HPA are collaborating with the Oxford Vaccine Group, the St Georges Vaccine Institute, the University of Southampton School of Medicine, the Bristol Children's Vaccine Centre and the Royal Devon and Exeter Hospital in a clinical trial of two vaccines against the Swine Flu (Novel Influenza A H1N1).  Recruitment and vaccination for this clinical trial will be conducted at five centres.  The role of the HPA will be to co-ordinate and manage data collection, to undertake testing of specimens obtained in the course of the trial and the statistical analysis.

For further information please visit www.swineflutrial.org.

Swine flu (Novel Influenza A H1N1) Vaccine Service Evaluation

The HPA are working with a few general practices in Hertfordshire and Gloucestershire as well as clinics at St Georges Hospital and Royal Marsden Hospital in London to provide a clinical service evaluation of the efficacy of the H1N1 vaccine provided to at risk groups in the national schedule.  This involves offering two or three blood tests to ascertain the individual's response to the vaccine. 

• Swine flu vaccine antibody response blood test option (Post) (PDF, 131 KB)