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Home Topics Infectious Diseases Infections A-Z Seasonal Influenza Epidemiological Data ›  Influenza Vaccine Composition

Influenza Vaccine Composition

Influenza vaccines are administered each year as new strains are evolving constantly.  To allow time for vaccine manufacture, the decision about which strains to include is made about six months in advance of the start of the influenza season.  The World Health Organization (WHO) makes recommendations twice a year for the northern hemisphere (usually February/March), and southern hemisphere (usually September) vaccine composition.  These recommendations are based on the strains circulating at the time, as reported by countries across the globe.  The WHO recommendations for the current and previous vaccines are listed on this page.  For more information, please visit the WHO website.

 

2012/2013 Influenza Season - Northern Hemisphere

It is recommended that vaccines for use in the 2012-2013 influenza season (northern hemisphere) contain the following:

  • an A/California/7/2009 (H1N1)pdm09-like virus;
  • an A/Victoria/361/2011 (H3N2)-like virus;
  • a B/Wisconsin/1/2010-like virus.

http://www.who.int/influenza/vaccines/virus/recommendations/2012_13_north/en/index.html

2012 Influenza Season - Southern Hemisphere

It is recommended that vaccines for use in the 2012 influenza season (southern hemisphere winter) contain the following:

  • an A/California/7/2009 (H1N1)pdm09-like virus;
  • an A/Perth/16/2009 (H3N2)-like virus;*
  • a B/Brisbane/60/2008-like virus.

* A/Wisconsin/15/2009 and A/Victoria/210/2009 are A/Perth/16/2009-like viruses.

http://www.who.int/influenza/vaccines/virus/recommendations/2012south/en/index.html

2011/2012 Influenza Season - Northern Hemisphere

It is recommended that vaccines for use in the 2011-2012 influenza season (northern hemisphere) contain the following:

  • an A/California/7/2009 (H1N1)-like virus;
  • an A/Perth/16/2009 (H3N2)-like virus;
  • a B/Brisbane/60/2008-like virus.

http://www.who.int/csr/disease/influenza/recommendations_2011_12north/en/index.html

2011 Influenza Season - Southern Hemisphere

It is recommended that vaccines for use in the 2011 influenza season (southern hemisphere winter) contain the following:

  • an A/California/7/2009 (H1N1)-like virus;
  • an A/Perth/16/2009 (H3N2)-like virus;*
  • a B/Brisbane/60/2008-like virus.

* A/Wisconsin/15/2009 and A/Victoria/210/2009 are A/Perth/16/2009-like viruses.

http://www.who.int/csr/disease/influenza/recommendations2011south/en/index.html

2010/11 Influenza Season - Northern Hemisphere

It is recommended that the following viruses be used for influenza vaccines in the 2010-2011 influenza season (northern hemisphere):

  • an A/California/7/2009 (H1N1)-like virus;
  • an an A/Perth/16/2009 (H3N2)-like virus;*
  • a B/Brisbane/60/2008-like virus.

* A/Wisconsin/15/2009 is an A/Perth/16/2009 (H3N2)-like virus and is a 2010 southern hemisphere vaccine virus.

http://www.who.int/csr/disease/influenza/recommendations2010_11north/en/index.html

2010 Influenza Season - Southern Hemisphere

It is recommended that vaccines for use in the 2010 influenza season (southern hemisphere winter) contain the following:

  • an A/California/7/2009 (H1N1)-like virus;
  • an A/Perth/16/2009 (H3N2)-like virus;
  • a B/Brisbane/60/2008-like virus.

http://www.who.int/csr/disease/influenza/recommendations2010south/en/index.html

2009/10 Influenza Season - Northern Hemisphere

The composition of the influenza vaccine for the 2009/2010 season (Northern Hemisphere winter) was announced by the World Health Organization in Geneva in February 2009.

It is recommended that vaccines contain the following:

  • an A/Brisbane/59/2007 (H1N1)-like virus;*
  • an A/Brisbane/10/2007 (H3N2)-like virus;**
  • a B/Brisbane/60/2008-like virus.#

* A/Brisbane/59/2007 is a current vaccine virus; A/South Dakota/6/2007 (an A/Brisbane/59/2007-like virus) is a current vaccine virus used in live attenuated vaccines.
** A/Brisbane/10/2007 and A/Uruguay/716/2007 (an A/Brisbane/10/2007-like virus) are current vaccine viruses.
# B/Brisbane/33/2008 is a B/Brisbane/60/2008-like virus.

2009 Influenza Season - Southern Hemisphere

The composition of the influenza vaccine for the 2009 season (Southern Hemisphere winter ) was announced by the World Health Organization in Geneva in September 2008.
It is recommended that vaccines contain the following:

  • an A/Brisbane/59/2007 (H1N1)-like virus;*
  • an A/Brisbane/10/2007 (H3N2)-like virus;**
  • a B/Florida/4/2006-like virus.#

* A/South Dakota/6/2007 (an A/Brisbane/59/2007-like virus) is a current vaccine virus used in live attenuated vaccines.

** A/Brisbane/10/2007 and A/Uruguay/716/2007 (an A/Brisbane/10/2007-like virus) are current vaccine viruses.

# B/Florida/4/2006 and B/Brisbane/3/2007 (a B/Florida/4/2006-like virus) are current vaccine viruses.

(Source WHO web page): http://www.who.int/csr/disease/influenza/recommendations2009south/en/index.html

2008/2009 Influenza Season - Northern Hemisphere

The composition of the influenza vaccine for the 2008/2009 season (Northern Hemisphere winter) was announced by the World Health Organization in Geneva in February 2008.

It is recommended that vaccines contain the following:

  • an A/Brisbane/59/2007 (H1N1)-like virus;
  • an A/Brisbane/10/2007 (H3N2)-like virus;*
  • a B/Florida/4/2006-like virus.#

* A/Brisbane/10/2007 is a current southern hemisphere vaccine virus.
# B/Florida/4/2006 and B/Brisbane/3/2007 (a B/Florida/4/2006-like virus) are current southern hemisphere vaccine viruses.

2008 Influenza Season - Southern Hemisphere

The composition of the influenza vaccine for the 2008 season (Southern Hemisphere winter) was announced by the World Health Organization in Geneva in September 2007.
It is recommended that vaccines contain the following:

  • an A/Solomon Islands/3/2006 (H1N1)-like virus*;
  • an A/Brisbane/10/2007 (H3N2)-like virus;
  • a B/Florida/4/2006-like virus.

*A/Solomon Islands/3/2006 is a current vaccine virus

2007/2008 Influenza Season - Northern Hemisphere

The composition of the influenza vaccine for the 2007/2008 season ( Northern Hemisphere winter) was announced by the World Health Organization in Geneva on the 15 February 2007.

It is recommended that vaccines contain the following:

  • an A/Solomon Islands/3/2006 (H1N1)-like virus
  • an A/Wisconsin/67/2005 (H3N2)-like virus*
  • a B/Malaysia/2506/2004-like virus

Candidate vaccine viruses include:
* A/Wisconsin/67/2005 (H3N2) and A/Hiroshima/52/2005

2007 Influenza Season - Southern Hemisphere

The composition of the influenza vaccine for the 2007 season ( Southern Hemisphere winter) was announced by the World Health Organization in Geneva in September 2006.

It is recommended that vaccines contain the following:

  • an A/New Caledonia/20/99(H1N1)-like virus
  • an A/Winconsin/67/2005(H3N2)-like virus,*
  • a B/Malaysia/2506/2004-like virus

*The currently used vaccine viruses are A/Winconsin/67/2005 and A/Hiroshima/52/2005.

2006/2007 Influenza Season - Northern Hemisphere

The composition of the influenza vaccine for the 2006/2007 season ( Northern Hemisphere winter) was announced by the World Health Organization in Geneva on the 14 February 2006. The A/H1N1component is unchanged from the 2005-06 northern hemisphere vaccine. The B component is the same as that used in the southern hemisphere 2005-06 vaccine

Accordingly, it is recommended that the vaccines to be used in the 2006-07 season (northern hemisphere winter) contain the following:

  • an A/New Caledonia/20/99 (H1N1)-like virus
  • an A/Wisconsin/67/2005 (H3N2)-like virus*
  • a B/Malaysia/2506/2004-like virus**

Candidate vaccine viruses include:
*A/Wisconsin/67/2005 (H3N2) and A/Hiroshima/52/2005
**B/Malaysia/2506/2004 virus and B/Ohio/1/2005

2006 Influenza Season - Southern Hemisphere

The composition of the influenza vaccine for the 2006 season, May - September ( Southern hemisphere winter) was announced by the World Health Organization in Geneva in September 2005. It is recommended that vaccines to be used in the 2006 season contain the following:

  • an A/New Caledonia/20/99(H1N1)-like virus;
  • an A/California/7/2004-(H3N2)-like virus*
  • a B/Malaysia/2506/2004-like virus

* The currently used vaccine virus is A/New York/55/2004

2005/2006 Influenza Season - Northern Hemisphere

The composition of the influenza vaccine for the 2005/2006 season ( Northern Hemisphere winter) was announced by the World Health Organization in Geneva on 10 February 2005.

The decision on the influenza A (H3N2) candidate vaccine virus was postponed pending the identification of a suitable high growth reassortant. The decision was made on 12 March 2005, and based on the results of antigenic and genetic analyses and growth in hen's eggs, a high growth reassortant virus derived from influenza A/New York/55/2004 (A/California/7/2004-like) virus and A/PR/8/34, has been identified as a suitable candidate influenza A (H3N2) vaccine virus.

Accordingly, it is recommended that the vaccine contain the following:

  • an A/New Caledonia/20/99(H1N1)-like virus
  • an A/California/7/2004-(H3N2)-like virus*
  • a B/Shanghai/361/2002-like virus**

* A/New York/55/2004 is available as a vaccine virus
** The currently used vaccine viruses are B/Shanghai/361/2002, B/Jiangsu/10/2003 and B/Jilin/20/2003.


Last reviewed: 28 August 2012