Immunoglobulin

Immunoglobulins are special concentrated antibody preparations which provide immediate short-term protection against disease for individuals who are at high risk of experiencing severe disease or of developing serious complications from the disease.

Human normal immunoglobulin preparations for hepatitis A, measles, polio and rubella and specific immunoglobulin preparations for hepatitis B, rabies and varicella-zoster for intramuscular use are issued by CDSC Immunisation Department and also by certain regional HPA and NHS laboratories.

The Immunoglobulin Handbook, written by experts in the Immunisation Department and their colleagues, contains information, indications and guidance for the use of these immunoglobulin preparations for each individual disease.

View the full version of reviewed Immunoglobulin handbook Immunoglobulin handbook - below are individual pdfs of each chapter Chapters currently not available separately. Please see above link for complete handbook

	Last review date
General information (PDF, 110 KB)	January 2007
Hepatitis A (PDF, 95 KB)	January 2007
Measles (PDF, 96 KB)	January 2007
Polio (PDF, 74 KB)	January 2007
Mumps (PDF, 68 KB)	January 2007
Rubella (PDF, 56 KB)	January 2007
Hepatitis B (PDF, 99 KB)	January 2007
Chickenpox (PDF, 155 KB)	January 2007
Diphtheria (PDF, 76 KB)	January 2007
Rabies (PDF, 83 KB)	January 2007
Tetanus (PDF, 111 KB)	January 2007
HPA recommendation on the treatment and prophylaxis of tetanus (PDF, 53 KB)	May 2008

• HBIG for babies born to hep b infected mothers (Word Document, 147 KB)
  policy on the use of HBIG for babies born to hep b infected mothers
  Added/updated: 3 October 2008