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LRU External Quality Control

External Quality Assurance (CPA Standard E6)

The Leptospira Reference Unit participates in the International Leptospirosis MAT proficiency testing scheme.

This scheme is a collaborative project of the Royal Tropical Institute, Amsterdam, the Leptospira Reference Unit, County Hospital, Hereford, and the National Serology Reference Laboratory, Melbourne, Australia and

The objectives of the scheme are (a) to provide participants with information about the quality of the MAT testing, as an aid to improve performance, and (b) to encourage a general improvement in the performance of MAT testing and in diagnosis of leptospirosis throughout the world.

Panels have been distributed to participants annually since 2002. After results are received, participants receive a preliminary report identifying samples, with a later comprehensive report, comparing and analysing results from different laboratories.

The LRU has participated in this scheme since 2002 with a consistently satisfactory performance.


Chappel, RJ., Goris, M., Palmer, MF., Hartskeerl, RA. 2004. Impact of Proficiency Testing on Results of the Microscopic Agglutination Test for Diagnosis of Leptospirosis. Journal of Clinical Microbiology 42, 5484-5488.

Last reviewed: 17 November 2010