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Home Publications Infectious diseases HIV and sexually transmitted infections Gonococcal Resistance to Antimcrobials Surveillance Programme ›  GRASP 2008 Report: Trends in Antimicrobial Resistant Gonorrhoea

GRASP 2008 Report: Trends in Antimicrobial Resistant Gonorrhoea

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Health Protection Agency

Publication date: June 2009



  • Resistance to third-generation cephalosporins, the current recommended first-line treatment for gonorrhoea, is emerging in England and Wales, and the first examples of reduced susceptibility to ceftriaxone were observed in 2008.
  • An apparent outbreak of high-level resistance to penicillin and tetracycline associated with sexual contact abroad emerged in 2007 and is ongoing in 2008.
  • Ciprofloxacin resistance is now endemic in England and Wales, accounting for 28% of all isolates tested in 2008.
  • Treatment of gonorrhoea is likely to become increasingly problematic as new types of resistance emerge.


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Additional information

Last reviewed: 26 January 2012