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Home Topics Radiation Radiation Advisory Groups Advisory Group on Ionising Radiation (AGIR)

Advisory Group on Ionising Radiation (AGIR)

 

Establishment and terms of reference

Public Health England (PHE) through its Centre for Radiation, Chemical and Environmental Hazards (CRCE) has a statutory responsibility for advising UK government departments, and those with responsibility for using ionising and non-ionising radiation, on the risks to human beings imposed by the use of such radiations. This applies in all areas: medical, public health, occupational and environmental. These responsibilities passed to PHE  from the Health Protection Agency (HPA) on its formation on 1 April 2013. HPA inherited the responsibility from the National Radiological Protection Board (NRPB) when it merged into the HPA on 1 April 2005. 

In 1995 the Director of NRPB set up the Advisory Group on Ionising Radiation (AGIR) that had as its terms of reference:

to review work on the biological and medical effects of ionising radiation relevant to human health in the occupational, public health, medical and environmental fields and advise on research priorities.

In addition, the AGIR has been given the task of helping PHE, where appropriate, deal with any urgent request for advice or work from the Department of Health or other government departments. The AGIR was reconstituted in 1999 as an independent body and reported directly to the Board of the NRPB; it now reports to the PHE Environmental Hazards Programme Board. The remit of the AGIR is restricted to the provision of scientific judgements and does not include the development of specific recommendations relating to radiation protection policy. These are matters for PHE and its Advisory Board.

The AGIR has now published ten reports covering a wide range of issues within its terms of reference:

  • genetic heterogeneity of response to radiation
  • guidance on the promotion of further optimisation of medical exposures
  • epidemiology of second cancer
  • reassessment of the risks of radiation-induced leukaemias and lymphomas in the UK population
  • risks from exposure to tritium
  • high-dose radiation effects and tissue injury
  • radon and public health
  • circulatory disease risk
  • solid cancer risk
  • human radiosensitivity.

For details of these reports see the Bibliography.

The AGIR was chaired from its start to 31 March 2013 by Professor Bryn Bridges OBE. His input has been instrumental in the development of the group and its work.

Main functions of the AGIR

  • to receive updates on progress in subgroups
  • to comment on subgroup reports at late stages of drafting
  • to make recommendations for subgroups on specific topics
  • to ensure that reports are subject to national and international peer review, as appropriate.

The AGIR meets annually unless urgent matters require attention. The detailed work of the AGIR is conducted within subgroups.

Planned developments

The current work programme of the AGIR was endorsed by the Environmental Hazards Technical Committee of the HPA Board in March 2012.

The AGIR maintains a watching brief on genomic instability and bystander effects and in March 2013 prepared a briefing note for the HPA on the topic of transgenerational effects of ionising radiation.

The work programme will be reviewed by the AGIR at its 2013 meeting.

Bibliography

AGIR (1999a). Genetic heterogeneity in the population and its implications for radiation risk. Report of an Advisory Group on Ionising Radiation. Doc NRPB, 10 (3), 1-47.

AGIR (1999b). Guidelines on patient doses to promote the optimisation of protection for diagniostic medical exposures. Report of an Advisory Group on Ionising Radiation. Doc NRPB, 10 (1), 1-43.

AGIR (2000). Risks of second cancer in therapeutically irradiated populations: comparison with cancer risks in the Japanese atomic bomb survivors and in other exposed groups. Report of an Advisory Group on Ionising Radiation. Doc NRPB, 11 (1), 1-105.

AGIR (2003). Risk of leukaemia and related malignancies following radiation exposure: estimates for the UK population. Report of an Advisory Group on Ionising Radiation. Doc NRPB, 14 (1), 1-119.

AGIR (2007), Review of risks from tritium. Report of the independent Advisory Group on Ionising Radiation. Chilton, Doc HPA, RCE-4, 1-90.

The HPA response to Review of risks from tritium is published here.

AGIR (2009a), High dose radiation effects and tissue injury.  Report of the independent Advisory Group on Ionising Radiation.  Chilton, Doc HPA,  RCE-10, 1-94.

AGIR (2009b), Radon and public health.  Report of the independent Advisory Group on Ionising Radiation.  Chilton, Doc. HPA, RCE-11,1-240.

AGIR (2010). Circulatory disease risk.  Report of the independent Advisory Group on Ionising Radiation.  Chilton, Doc HPA, RCE-16, 1-116.

The HPA response to Circulatory disease risk is published here.

AGIR (2011). Risk of solid cancers following radiation exposure: estimates for the UK population. Report of the independent Advisory Group on Ionising Radiation. Chilton, Doc HPA, RCE-19, 1-258.

AGIR (2013a). Evidence for Transgenerational Effects Following Exposure to Ionising Radiation. A briefing note prepared by a subgroup of the Advisory Group on Ionising Radiation. Chilton.

AGIR (2013b). Human radiosensitivity. Report of the Independent Advisory Group on Ionising Radiation. Chilton, Doc HPA, RCE-21, 1-152. 

Membership

Chairman

Dr Dudley Goodhead, OBE, MRC Harwell (acting Chair from 1 April 2013)

Members

Professor Peter Hoskin, University College London Hospitals
Dr Mark Little, US National Cancer Institute, Bethesda
Professor Trevor McMillan, Lancaster University

Secretariat

Dr Simon Bouffler, PHE

Observers

Dr Hilary Walker, Department of Health
Dr Stuart Conney, Department of Health

Invitation to submit published work for consideration

The AGIR welcomes the submission of references to published work relevant to the current work programme. Please send details to

simon.bouffler@phe.gov.uk

AGIR Secretariat
PHE Centre for Radiation, Chemical and Environmental Hazards
Chilton
Didcot
Oxfordshire OX11 ORQ

It will be for the AGIR and subgroup members to decide what weight to give the submitted material and whether or not to cite it.


Last reviewed: 5 August 2013