Skip to main content
hpa logo
Topics A-Z:
Search the site:
Home Products & Services Microbiology and Pathology Laboratories and Reference Facilities Respiratory and Vaccine Preventable Bacteria Reference Unit

Respiratory and Vaccine Preventable Bacteria Reference Unit


(Image supplied courtesy of Dr A Efstratiou)

Respiratory and Vaccine Preventable Bacteria Reference Unit (RVPBRU)
Public Health England
Microbiology Services Colindale
61 Colindale Avenue
London NW9 5HT

Hays DX address
Bacteriology Reference Department
Colindale NW

Tel: 020 8200 4400 

The Respiratory and Vaccine Preventable Bacteria Reference Unit (RVPBRU) is part of PHE Microbiology Services, Colindale, London.

RVPBRU is a national and international reference laboratory for a number of bacteria responsible for respiratory and systemic infection and receives bacterial isolates and clinical samples, eg urines, from PHE, National Health Service and commercial laboratories throughout the UK. The diagnostic and reference samples received are analysed by a wide range of methodologies in accordance with customer needs.

The laboratory includes the PHE Reference Units for streptococci, diphtheria, haemophili, mycoplasma, legionella, respiratory chlamydiae and bordetella. The first three of these units are WHO Collaborating Centres and as such provide laboratory and advisory support for national (and other) centres worldwide. The laboratory and its staff work closely with other colleagues in PHE-MS and beyond on the diagnosis and surveillance of infections within its remit.

RVPBRU is resourced to provide a range of free of charge reference services to NHS and PHE laboratories in England and Wales. A number of referred (charged for services) associated with primary diagnostic activity are also provided to NHS and PHE laboratories in England and Wales, and these are subject to a charge. Tests provided to laboratories in England and Wales, for which a charge is levied, are indicated as such in the relevant sections of the User Manual. All submissions for both reference and referred testing from laboratories outside England and Wales are subject to charging. Please note this includes all work undertaken for Scotland, Northern Ireland, the Channel Islands and the Republic of Ireland.

For enquiries regarding the level of charging for individual tests, please contact the laboratory director and or Unit Heads for the details.